| Identification | Back Directory | [Name]
NALTRIBEN MESYLATE | [CAS]
111555-58-9 | [Synonyms]
NTB
NALTRIBEN MESYLATE
naltrindolebenzofuran
NALTRIBEN METHANESULFONATE
17-(Cyclopropylmethyl)-6,7-didehydro-3,14β-dihydroxy-4,5α-epoxy-6,7-2',3'-benzo[b]furanomorphinanmesylate
17-(Cyclopropylmethyl)-6,7-didehydro-3,14b-dihydroxy-4,5a-epoxy-6,7-2',3'-benzo[b]furanomorphinanmesylate
17-(CYCLOPROPYLMETHYL)-6,7-DIDEHYDRO-3, 14B-DIHYDROXY-4,5A-EPOXY-6,7-2',3'-BENZO[B]FURANOMORPHINAN MESYLATE
17-(Cyclopropylmethyl)-6,7-didehydro-3-4,5alpha-epoxy-14beta-dihydroxy-6,7-2',3'-benzo[b]furanomorphinan mesylate
4,8-Methano-8aH-bisbenzofuro[3,2-e:2',3'-g]isoquinoline-1,8a-diol, 7-(cyclopropylmethyl)-5,6,7,8,9,14b-hexahydro-, (4bS,8R,8aS,14bR)- | [Molecular Formula]
C26H25NO4 | [MDL Number]
MFCD00673953 | [MOL File]
111555-58-9.mol | [Molecular Weight]
415.48 |
| Chemical Properties | Back Directory | [Boiling point ]
605.3±55.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: 14 mg/mL at ~60 °C | [form ]
solid | [pka]
9.30±0.40(Predicted) | [color ]
off-white |
| Hazard Information | Back Directory | [Uses]
Naltriben is a potent and selective antagonist for the δ2 opioid receptor. Naltriben is used to differentiate the δ1 and δ2 opioid receptors. | [Definition]
ChEBI: Naltriben is a morphinane alkaloid. | [Biological Activity]
Selective and potent δ -opioid receptor antagonist (K i values are 0.013, 19 and 152 nM for δ , μ and κ receptors respectively). Displays selectivity for the δ 2 subtype in vivo . |
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