| Identification | Back Directory | [Name]
MEOSUC-ALA-ALA-PRO-ALA-CHLOROMETHYLKETONE | [CAS]
111682-13-4 | [Synonyms]
MSACK
HNE INHIBITOR
MEOSUC-AAPA-CMK
ELASTASE INHIBITOR II
MEOSUC-ALA-ALA-PRO-ALA-CMK
Neutrophil elastase inhibitor 2
MEOSUC-ALA-ALA-PRO-ALA-CHLOROMETHYLKETONE
methoxysuccinyl-Ala-Ala-Pro-Ala chloromethyl ketone
methoxysuccinyl-alanyl-alanyl-prolyl-alaninechloromethylketone
L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-methyl-2-oxopropyl]- | [Molecular Formula]
C20H31ClN4O7 | [MDL Number]
MFCD00238296 | [MOL File]
111682-13-4.mol | [Molecular Weight]
474.94 |
| Chemical Properties | Back Directory | [Boiling point ]
810.8±65.0 °C(Predicted) | [density ]
1.269±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [solubility ]
Soluble in methanol or DMSO | [form ]
lyophilized solid | [pka]
13.13±0.20(Predicted) | [color ]
white | [Sensitive ]
Moisture Sensitive |
| Hazard Information | Back Directory | [Uses]
A potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His57 and Ser195 in the HNE in the presence of this inhibitor.
A potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His57 and Ser195. | [Definition]
ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Ala by conversion of the terminal carboxy group to the corresponding chloromethyl ketone. | [Biological Activity]
Primary Target
Human neutrophil elastase (HNE) |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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