| Identification | Back Directory | [Name]
HSV-TK substrate | [CAS]
111687-37-7 | [Synonyms]
HSV-TK substrate 6H-Purin-6-one, 2-amino-9-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro- | [Molecular Formula]
C11H15N5O4 | [MDL Number]
MFCD32197219 | [MOL File]
111687-37-7.mol | [Molecular Weight]
281.27 |
| Hazard Information | Back Directory | [Uses]
HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. HSV-TK substrate shows antitumor activity[1]. | [storage]
Store at -20°C | [References]
[1] Shewach DS, et al. Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells. Hum Gene Ther. 2002 Mar 1;13(4):543-51. DOI:10.1089/10430340252809838 |
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