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111864-49-4

111864-49-4 Structure

111864-49-4 Structure
IdentificationBack Directory
[Name]

Adenosine 5'-(trihydrogen diphosphate), 2'-deoxy-, P'→5-ester with D-ribose
[CAS]

111864-49-4
[Synonyms]

Adenosine 5'-(trihydrogen diphosphate), 2'-deoxy-, P'→5-ester with D-ribose
[Molecular Formula]

C15H23N5O13P2
[MOL File]

111864-49-4.mol
[Molecular Weight]

543.32
Chemical PropertiesBack Directory
[Boiling point ]

935.0±75.0 °C(Predicted)
[density ]

2.15±0.1 g/cm3(Predicted)
[pka]

1.13±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

2′-Deoxy-ADPR is an agonist for transient receptor potential melastatin 2 channel (TRPM2 channel). 2′-Deoxy-ADPR may acts as the signaling molecule in Jurkat T-lymphocytes[1].
[References]

[1] Fliegert R, et al., 2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist. Nat Chem Biol. 2017 Sep;13(9):1036-1044. DOI:10.1038/nchembio.2415
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