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1119831-25-2

1119831-25-2 Structure

1119831-25-2 Structure
IdentificationBack Directory
[Name]

3-(1-((3,5-DIMETHYLISOXAZOL-4-YL)METHYL)-1H-PYRAZOL-4-YL)-1-(3-HYDROXYBENZYL)IMIDAZOLIDINE-2,4-DIONE
[CAS]

1119831-25-2
[Synonyms]

3-(1-((3,5-DIMETHYLISOXAZOL-4-YL)METHYL)-1H-PYRAZOL-4-YL)-1-(3-HYDROXYBENZYL)IMIDAZOLIDINE-2,4-DIONE
[Molecular Formula]

C19H19N5O4
[MOL File]

1119831-25-2.mol
[Molecular Weight]

381.385
Chemical PropertiesBack Directory
[FEMA ]

4725 | 3-(1-((3,5-DIMETHYLISOXAZOL-4-YL)METHYL)-1H-PYRAZOL-4-YL)-1-(3-HYDROXYBENZYL)IMIDAZOLIDINE-2,4-DIONE
[form ]

Solid
[color ]

Off-white to pink
[Odor]

bland
[JECFA Number]

2161
Hazard InformationBack Directory
[Uses]

S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo[1].
[References]

[1] Karanewsky DS, et al. Toxicological evaluation of two novel bitter modifying flavour compounds: 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione and 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione. Toxicol Rep. 2016 Feb 28;3:310-327. DOI:10.1016/j.toxrep.2016.02.007
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