| Identification | Back Directory | [Name]
3-(1-((3,5-DIMETHYLISOXAZOL-4-YL)METHYL)-1H-PYRAZOL-4-YL)-1-(3-HYDROXYBENZYL)IMIDAZOLIDINE-2,4-DIONE | [CAS]
1119831-25-2 | [Synonyms]
3-(1-((3,5-DIMETHYLISOXAZOL-4-YL)METHYL)-1H-PYRAZOL-4-YL)-1-(3-HYDROXYBENZYL)IMIDAZOLIDINE-2,4-DIONE | [Molecular Formula]
C19H19N5O4 | [MOL File]
1119831-25-2.mol | [Molecular Weight]
381.385 |
| Hazard Information | Back Directory | [Uses]
S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo[1]. | [References]
[1] Karanewsky DS, et al. Toxicological evaluation of two novel bitter modifying flavour compounds: 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione and 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione. Toxicol Rep. 2016 Feb 28;3:310-327. DOI:10.1016/j.toxrep.2016.02.007 |
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DC Chemicals
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