| Identification | Back Directory | [Name]
Adenosine, 5′-[N-[(2S)-2-amino-4-(methylthio)-1-oxobutyl]sulfamate], compd. with N,N-diethylethanamine (1:1) | [CAS]
1122489-97-7 | [Synonyms]
Adenosine, 5′-[N-[(2S)-2-amino-4-(methylthio)-1-oxobutyl]sulfamate], compd. with N,N-diethylethanamine (1:1) | [Molecular Formula]
C15H23N7O7S2.C6H15N | [MOL File]
1122489-97-7.mol | [Molecular Weight]
578.71 |
| Hazard Information | Back Directory | [Uses]
Met-AMS TEA (compound 50), a sulfamate analogue of methionyl adenylate, is a potent Escherichia coli methionyl-tRNA synthetase (MetRS) inhibitor (IC50 of 7 nM)[1]. | [References]
[1] Jeewoo Lee, et al. N-Alkoxysulfamide, N-hydroxysulfamide, and sulfamate analogues of methionyl and isoleucyl adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1087-92. DOI:10.1016/s0960-894x(03)00020-9 |
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