ChemicalBook--->CAS DataBase List--->1123491-15-5

1123491-15-5

1123491-15-5 Structure

1123491-15-5 Structure
IdentificationBack Directory
[Name]

5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
[CAS]

1123491-15-5
[Synonyms]

DMPQ (hydrochloride)
[Molecular Formula]

C16H16Cl2N2O2
[MDL Number]

MFCD02262123
[MOL File]

1123491-15-5.mol
[Molecular Weight]

339.216
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[solubility ]

H2O: >10mg/mL
[form ]

powder
[color ]

white to beige
[Water Solubility ]

Soluble to 100 mM in water
[InChI]

1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H
[InChIKey]

YBBAOKYVJCNJIV-UHFFFAOYSA-N
[SMILES]

Cl.Cl.COc1cc(OC)c2cc(cnc2c1)-c3ccncc3
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Hazard InformationBack Directory
[Uses]

DMPQ dihydrochloride is a selective an a potent inhibitor of human platelet-derived growth factor receptor β (PDGFRβ).
[Biological Activity]

DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR?) with IC50 = 80 nM. It is > 100-fold selective over EGFRerbB2p56protein kinase A and protein kinase C.
[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride(1123491-15-5)1HNMR
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