ChemicalBook--->CAS DataBase List--->112430-63-4

112430-63-4

112430-63-4 Structure

112430-63-4 Structure
IdentificationBack Directory
[Name]

ganodermic acid S
[CAS]

112430-63-4
[Synonyms]

ganodermic acid S
(24E)-3β,15α-Bis(acetyloxy)lanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oic acid, 3,15-bis(acetyloxy)-, (3β,15α,24E)-
(E,6R)-6-[(3S,10S,13R,14R,15S,17R)-3,15-diacetyloxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoicaci
[Molecular Formula]

C34H50O6
[MOL File]

112430-63-4.mol
[Molecular Weight]

554.77
Chemical PropertiesBack Directory
[Boiling point ]

633.8±55.0 °C(Predicted)
[density ]

1.12±0.1 g/cm3(Predicted)
[pka]

5.01±0.19(Predicted)
Hazard InformationBack Directory
[Description]

Ganodermic acid S, a membrane acting agent, exerts multiple effects on human platelet function. Ganodermic acid S is isolated from the Chinese medicinal fungus Ganoderma lucidum.
[Uses]

Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic[1].
[References]

[1] Su CY, et al. Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets. Biochem Pharmacol. 1999 Aug 15;58(4):587-95. DOI:10.1016/s0006-2952(99)00136-7
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