ChemicalBook--->CAS DataBase List--->112501-42-5

112501-42-5

112501-42-5 Structure

112501-42-5 Structure
IdentificationBack Directory
[Name]

Aristolactam FI
[CAS]

112501-42-5
[Synonyms]

PiperolactamA
Aristolactam FI
Dibenz[cd,f]indol-4(5H)-one,1-hydroxy-2-methoxy-
[Molecular Formula]

C16H11NO3
[MDL Number]

MFCD20274568
[MOL File]

112501-42-5.mol
[Molecular Weight]

265.26
Chemical PropertiesBack Directory
[Melting point ]

>300 °C
[Boiling point ]

457.0±38.0 °C(Predicted)
[density ]

1.441±0.06 g/cm3(Predicted)
[pka]

8.39±0.20(Predicted)
[InChI]

InChI=1S/C16H11NO3/c1-20-12-7-10-13-11(17-16(10)19)6-8-4-2-3-5-9(8)14(13)15(12)18/h2-7,18H,1H3,(H,17,19)
[InChIKey]

KBGNBPGXVKPRQI-UHFFFAOYSA-N
[SMILES]

N1C2=C3C(C(O)=C(OC)C=C3C1=O)=C1C=CC=CC1=C2
Hazard InformationBack Directory
[Uses]

Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani[1].
[Definition]

ChEBI: Piperolactam A is an alkaloid.
[IC 50]

Leishmania
[References]

[1] Bhattacharya P, et al. In Vitro susceptibilities of wild and drug resistant Leishmania donovani amastigotes to piperolactam A loaded hydroxypropyl-β-cyclodextrin nanoparticles. Acta Trop. 2016 Jun;158:97-106. DOI:10.1016/j.actatropica.2016.02.017
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