ChemicalBook--->CAS DataBase List--->112649-21-5

112649-21-5

112649-21-5 Structure

112649-21-5 Structure
IdentificationBack Directory
[Name]

Garcinone E
[CAS]

112649-21-5
[Synonyms]

Garcinone E
7-O-Demethyl-5-prenyl-alpha-mangostin
2,3,6,8-Tetrahydroxy-1,4,7-tris(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
9H-Xanthen-9-one,2,3,6,8-tetrahydroxy-1,4,7-tris(3-methyl-2-buten-1-yl)-
[Molecular Formula]

C28H32O6
[MDL Number]

MFCD12756397
[MOL File]

112649-21-5.mol
[Molecular Weight]

464.55
Chemical PropertiesBack Directory
[Boiling point ]

694.9±55.0 °C(Predicted)
[density ]

1.240±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

7.20±0.20(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas[1].
[Definition]

ChEBI: Garcinone E is a member of xanthones.
[References]

[1] Linli Yang, et al. Garcinone-E exhibits anticancer effects in HeLa human cervical carcinoma cells mediated via programmed cell death, cell cycle arrest and suppression of cell migration and invasion. AMB Express. 2020 Jul 16;10(1):126. DOI:10.1186/s13568-020-01060-0
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