| Identification | Back Directory | [Name]
Garcinone E | [CAS]
112649-21-5 | [Synonyms]
Garcinone E
7-O-Demethyl-5-prenyl-alpha-mangostin
2,3,6,8-Tetrahydroxy-1,4,7-tris(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
9H-Xanthen-9-one,2,3,6,8-tetrahydroxy-1,4,7-tris(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C28H32O6 | [MDL Number]
MFCD12756397 | [MOL File]
112649-21-5.mol | [Molecular Weight]
464.55 |
| Chemical Properties | Back Directory | [Boiling point ]
694.9±55.0 °C(Predicted) | [density ]
1.240±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
7.20±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas[1]. | [Definition]
ChEBI: Garcinone E is a member of xanthones. | [References]
[1] Linli Yang, et al. Garcinone-E exhibits anticancer effects in HeLa human cervical carcinoma cells mediated via programmed cell death, cell cycle arrest and suppression of cell migration and invasion. AMB Express. 2020 Jul 16;10(1):126. DOI:10.1186/s13568-020-01060-0 |
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