| Identification | Back Directory | [Name]
1-(4-CHLORO-2-HYDROXYPHENYL)PROPAN-1-ONE | [CAS]
1127-97-5 | [Synonyms]
4'-chloro-2'-hydroxypropiophenone
1-(4-CHLORO-2-HYDROXYPHENYL)PROPAN-1-ONE
1-Propanone, 1-(4-chloro-2-hydroxyphenyl)- | [Molecular Formula]
C9H9ClO2 | [MDL Number]
MFCD00218578 | [MOL File]
1127-97-5.mol | [Molecular Weight]
184.62 |
| Hazard Information | Back Directory | [Preparation]
Preparation by Fries rearrangement of m-chlo- rophenyl propionate (b.p.0.8 90°) with aluminium chloride,
without solvent at 100° for 2 h (92%), at 140° for 2 h (89%), ? at 140–150° for 3 h, at 130° for 2 h (77%), at 165° for 1 h (72%), at 50° for 3 h (55%) or at 30–40° (53%)
n nitrobenzene at 25° for 6 h (87%)
Preparation by Fries rearrangement of m-chlorophenyl propionate with titanium tetrachloride at 100° for 2 h (75%)
Also obtained by Friedel–Crafts reaction of propionyl chloride with m-chlorophenol in the presence of aluminium chloride
Also obtained by isomerization of 2-chloro-4-hydroxypropiophenone on heating with aluminium chloride between 165° and 200° (30–70%). |
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Matrix Scientific
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803 788-9494 All other calls |
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www.matrixscientific.com |
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