ChemicalBook--->CAS DataBase List--->112972-60-8

112972-60-8

112972-60-8 Structure

112972-60-8 Structure
IdentificationBack Directory
[Name]

BISUCABERIN
[CAS]

112972-60-8
[Synonyms]

Biscaberin
BISUCABERIN
6,17-Dihydroxy-1,6,12,17-tetraazacyclodocosane-2,5,13,16-tetrone
1,6,12,17-Tetraazacyclodocosane-2,5,13,16-tetrone, 1,12-dihydroxy-
[Molecular Formula]

C18H32N4O6
[MDL Number]

MFCD08457926
[MOL File]

112972-60-8.mol
[Molecular Weight]

400.47
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO: soluble
[form ]

A crystalline solid
Hazard InformationBack Directory
[Uses]

Bisucaberin is a natural siderophore, is a DNA synthesis inhibitor. Bisucaberin shows cytostasis for tumor cells. Bisucaberin sensitizes tumor cells to macrophage-mediated cytolysis[1].
[Definition]

ChEBI:1,12-Dihydroxy-1,6,12,17-tetraazacyclodocosane-2,5,13,16-tetrone is a keratan 6'-sulfate and an azamacrocycle.
[storage]

-20°C
[References]

[1] T Kameyama, et al. Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. I. Taxonomy of the producing organism, isolation and biological properties. J Antibiot (Tokyo). 1987 Dec;40(12):1664-70. DOI:10.7164/antibiotics.40.1664
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