| Identification | Back Directory | [Name]
Physalin L | [CAS]
113146-74-0 | [Synonyms]
PHYSALIN L(P)
1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,8aH)-tetrone, 2,3,6,6a,9,10,10a,10b,12,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,3,6a,10b-tetramethyl-, (1S,2S,3S,6R,6aS,8aR,10aS,10bR,16R,16aS,17R,18aR)- | [Molecular Formula]
C28 H32 O10 | [MOL File]
113146-74-0.mol | [Molecular Weight]
528.55 |
| Chemical Properties | Back Directory | [Boiling point ]
831.1±65.0 °C(Predicted) | [density ]
1.53±0.1 g/cm3 (20 ºC 760 Torr) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
9.87±0.70(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Chemical Properties]
White powder, easily soluble in methanol, almost insoluble in ether, extracted from the inside of Physalis alkekengi, the persistent calyx of Physalis alkekengi (Physalis alkekengi) or the persistent calyx with fruit. | [Uses]
Physalin L inhibits LPS-induced NO production in macrophages with the average inhibitory rate of 70.97%. Anti-inflammatory activity[1]. | [Definition]
ChEBI: Physalin L is a physalin. | [References]
[1] Long Ji, et al. Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids. 2012 Apr;77(5):441-7. DOI:10.1016/j.steroids.2011.11.016 |
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