| Identification | Back Directory | [Name]
ALW-II-49-7 | [CAS]
1135219-23-6 | [Synonyms]
ALW-II-49-7
3-Pyridinecarboxamide, 5-[[2-methyl-5-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]amino]- | [Molecular Formula]
C21H17F3N4O2 | [MOL File]
1135219-23-6.mol | [Molecular Weight]
414.38 |
| Chemical Properties | Back Directory | [Boiling point ]
522.8±50.0 °C(Predicted) | [density ]
1.399±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.22±0.70(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC50 value of 40 nM in cell[1]. | [Definition]
ChEBI: 5-[2-methyl-5-[oxo-[3-(trifluoromethyl)anilino]methyl]anilino]-3-pyridinecarboxamide is a member of benzamides. | [References]
[1] Choi Y, et al. Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4467-70. DOI:10.1016/j.bmcl.2009.05.029 |
|
|