| Identification | Back Directory | [Name]
7-Hydroxy CouMarin Sulfate | [CAS]
1135316-80-1 | [Synonyms]
SVUZPRLQAASRKC-UHFFFAOYSA-M
7-Hydroxy coumarin sulfate (potassium)
7-Hydroxy Coumarin Sulphate Potassium Salt | [Molecular Formula]
C9H8O7S | [MOL File]
1135316-80-1.mol | [Molecular Weight]
260.221 |
| Hazard Information | Back Directory | [Description]
7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS. | [Chemical Properties]
Pale-Yellow Solid | [Uses]
Metabolite | [Uses]
Metabolite of 7-hydroxycoumarin (7-HC). Found in hepatocyte, microsome, S9 fraction of human, dog, monkey, rat and mouse liver. | [storage]
Store at -20°C | [References]
[1] S EKINS. Xenobiotic metabolism in rat, dog, and human precision-cut liver slices, freshly isolated hepatocytes, and vitrified precision-cut liver slices.[J]. Drug Metabolism and Disposition, 1996, 24 9: 990-995.
[2] QING WANG. Glucuronidation and sulfation of 7-hydroxycoumarin in liver matrices from human, dog, monkey, rat, and mouse.[J]. In Vitro Cellular & Developmental Biology. Animal, 2005, 41 3-4: 97-103. DOI: 10.1290/0501005.1
[3] MING-CHIH DAVID HO. Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors.[J]. Drug Metabolism and Disposition, 2017, 45 6: 686-691. DOI: 10.1124/dmd.116.074377
[4] JOEL R. L. EHRENKRANZ. Phlorizin: a review[J]. Diabetes/Metabolism Research and Reviews, 2004, 21 1: 31-38. DOI: 10.1002/dmrr.532 |
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Energy Chemical
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