| Identification | Back Directory | [Name]
L-Argininamide, N2-[(phenylmethoxy)carbonyl]-L-lysyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | [CAS]
1135364-14-5 | [Synonyms]
Z-Nle-Lys-Arg-AMC acetate
L-Argininamide, N2-[(phenylmethoxy)carbonyl]-L-lysyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | [Molecular Formula]
C36H51N9O7 | [MOL File]
1135364-14-5.mol | [Molecular Weight]
721.85 |
| Hazard Information | Back Directory | [Uses]
Z-Nle-Lys-Arg-AMC is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range[1]. | [References]
[1] Yoon MC, et al. Distinct Cleavage Properties of Cathepsin B Compared to Cysteine Cathepsins Enable the Design and Validation of a Specific Substrate for Cathepsin B over a Broad pH Range. Biochemistry. 2023 Aug 1;62(15):2289-2300. DOI:10.1021/acs.biochem.3c00139 |
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