ChemicalBook--->CAS DataBase List--->1135688-47-9

1135688-47-9

1135688-47-9 Structure

1135688-47-9 Structure
IdentificationBack Directory
[Name]

Z-AEVD-FMK
[CAS]

1135688-47-9
[Synonyms]

Z-AEVD-FMK
Z-AVED-FMK
Z-AE(OME)VD(OME)-FMK
CHZRBQFKZDGMTP-CDSYHYPYSA-N
GROUP III CASPASE INHIBITOR I
Z-ALA-GLU(OME)-VAL-ASP(OME)-FMK
Z-AE(OME)VD(OME)-FMK (FLUOROMETHYL)
Z-ALA-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE
[Molecular Formula]

C28H39FN4O10
[MDL Number]

MFCD03453601
[MOL File]

1135688-47-9.mol
[Molecular Weight]

610.63
Chemical PropertiesBack Directory
[Boiling point ]

883.7±65.0 °C(Predicted)
[density ]

1.236±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 10 mg/ml*
[form ]

A crystalline solid
[pka]

11.12±0.46(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

(5S,8S,11S,14S)-Methyl 14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate is a caspase-10 inhibitor.
[Biological Activity]

Cell permeable: yes''Primary Target
caspase-1caspase-3caspase-6caspase-8caspase-9caspase-10''Product does not compete with ATP.''Reversible: no
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