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113578-26-0

113578-26-0 Structure

113578-26-0 Structure
IdentificationBack Directory
[Name]

M-NISOLDIPINE
[CAS]

113578-26-0
[Synonyms]

M-NISOLDIPINE
m-Nisolpidine
4-dihydropyridine-3
m Nisoldipine,mNisoldipine
3-methyl 5-(2-methylpropyl) 2
6-dimethyl-4-(3-nitrophenyl)-1
3-Methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-(2-methylpropyl) ester
[Molecular Formula]

C20H24N2O6
[MDL Number]

MFCD09837745
[MOL File]

113578-26-0.mol
[Molecular Weight]

388.41
Chemical PropertiesBack Directory
[Melting point ]

122-124 °C
[Boiling point ]

505.8±50.0 °C(Predicted)
[density ]

1.205±0.06 g/cm3(Predicted)
[pka]

2.69±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

m-Nisoldipine (KR-1008) is a dihydropyridine calcium antagonist that can significantly increase cardiac output and heart index, significantly reduce the negative inotropic effect on the myocardium, and has a relatively high selectivity for the thoracic aorta. m-Nisoldipine can be used in the research of cardiovascular diseases[1].
[Definition]

ChEBI: M-Nisoldipine is a dihydropyridine.
[References]

[1] Yang C, et al. Thermodynamic stability analysis of m-nisoldipine polymorphs[J]. The Journal of Chemical Thermodynamics, 2013, 58: 300-306.
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