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113714-78-6

113714-78-6 Structure

113714-78-6 Structure
IdentificationBack Directory
[Name]

Ro 23-7014
[CAS]

113714-78-6
[Synonyms]

Ro 23-7014
[Molecular Formula]

C48H63N9O16S4
[MOL File]

113714-78-6.mol
[Molecular Weight]

1150.32
Chemical PropertiesBack Directory
[density ]

1.424±0.06 g/cm3(Predicted)
[pka]

-4.16±0.18(Predicted)
[Sequence]

Ac-{Tyr(SO3H)}-Met-Gly-Trp-Met-{Thr(SO3H)}-{N-methyl-Phe}-NH2
Hazard InformationBack Directory
[Description]

Ro 23-7014 is a new thiazepinone Ca2+ channel antagonist that has high affinity for peripheral (Type A) receptors.
[Uses]

Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7)[1].
[References]

[1] Danho W, et al. Synthesis and biological activity of novel, potent and long-acting analogs of AC-CCK-7 with high affinity for peripheral (type A) receptors. Pept Res. 1991 Mar-Apr;4(2):59-65. PMID:1815779
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