| Identification | Back Directory | [Name]
BOC-GRR-AMC | [CAS]
113866-14-1 | [Synonyms]
BOC-GRR-AMC
BOC-GLY-ARG-ARG-MCA
BOC-GLY-ARG-ARG-AMC
T-BUTYLOXYCARBONYLGLYCYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
TERT-BUTYLOXYCARBONYL-GLYCYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
tert-butyl N-[2-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]carbamate | [Molecular Formula]
C29H44N10O7 | [MDL Number]
MFCD00080221 | [MOL File]
113866-14-1.mol | [Molecular Weight]
644.72 |
| Hazard Information | Back Directory | [Uses]
Boc-GRR-AMC is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity[1][2]. | [References]
[1] Nancy Lee, et al. Characterization of metacaspases with trypsin-like activity and their putative role in programmed cell death in the protozoan parasite Leishmania. Eukaryot Cell. 2007 Oct;6(10):1745-57. DOI:10.1128/EC.00123-07
[2] Manolya Ezgimen, et al.Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease. Antiviral Res. 2012 Apr;94(1):18-24. DOI:10.1016/j.antiviral.2012.02.003 |
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