| Identification | Back Directory | [Name]
1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione | [CAS]
114262-49-6 | [Synonyms]
Sofosbuvir metabolites GS331007
Sofosbuvir Methylarabinosyl Impurity
Hydroxyuridine/Sofosbuvir Impurity 12
1-β-D-Arabinofuranosyluracil-2-C-methyl
1-(2'-C-methyl-β-D-arabinofuranosyl)uracil
1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 1-(2-C-methyl-β-D-arabinofuranosyl)-
1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione | [Molecular Formula]
C10H14N2O6 | [MOL File]
114262-49-6.mol | [Molecular Weight]
258.23 |
| Hazard Information | Back Directory | [Uses]
1-β-D-Arabinofuranosyluracil-2-C-methyl is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
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SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
| Company Name: |
BOC Sciences
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16314854226 |
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www.bocsci.com |
| Company Name: |
PI & PI BIOTECH INC.
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+86-13602409664 +86-17788709170 |
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www.paypaytech.com/ |
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