ChemicalBook--->CAS DataBase List--->1144107-78-7

1144107-78-7

1144107-78-7 Structure

1144107-78-7 Structure
IdentificationBack Directory
[Name]

Cyanine7 carboxylic acid
[CAS]

1144107-78-7
[Synonyms]

Cyanine7-COOH
Cyanine7 carboxylic acid
[Molecular Formula]

C34H40N2O2
[MOL File]

1144107-78-7.mol
[Molecular Weight]

508.71
Chemical PropertiesBack Directory
[solubility ]

易溶于DMF等有机溶剂
[Appearance]

Green solid
[ex/em]

740/770 nm (MeOH/PBS)
[ε(extinction coefficient)]

199000 L⋅mol−1⋅cm−1
[Φ(quantum yield)]

0.3
[InChIKey]

MQMHUMKZLAOASA-UHFFFAOYSA-N
[SMILES]

C(N1C(C(C)(C)C2=CC=CC=C12)=CC=CC=CC=CC1C(C2=CC=CC=C2[N+]=1C)(C)C)CCCCC(=O)[O-]
Hazard InformationBack Directory
[Description]

The unactivated free carboxylic acid of near-infrared fluorescent dye Cyanine7. For coupling and labeling reactions also consider using pre-activated Cyanine7 NHS ester, or water-soluble sulfo-Cyanine7 NHS ester.

[Chemical Properties]

Appearance: Green solid
ex/em: 740/770 nm (MeOH/PBS)
Extinction coefficient (ε): 199000 L??mol??1??cm??1
Quantum yield (Φ): 0.3
[Uses]

Cyanine7 carboxylic acid (Cy7 COOH) is a derivative of Cy7 (HY-D0825) dye. Cyanine7 carboxylic acid contains carboxyl groups, which can condense ammonia to form covalent bonds[1].
[References]

[1] Zhang X, et al. Highly stable near-infrared dye conjugated cerasomes for fluorescence imaging-guided synergistic chemo-photothermal therapy of colorectal cancer. Biomater Sci. 2019 Jul 1;7(7):2873-2888. DOI:10.1039/c9bm00458k
[Abs/Em Maxima]

750/773 nm
[Extinction Coefficient]

199000
[CF260]

0.022
[CF280]

0.029
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