| Identification | Back Directory | [Name]
5H-Quinindoline,5-methyl- | [CAS]
114414-78-7 | [Synonyms]
new cryptolepine
5H-Quinindoline,5-methyl-
5-methylindolo[2,3-b]quinoline | [Molecular Formula]
C16H12N2 | [MDL Number]
MFCD29042406 | [MOL File]
114414-78-7.mol | [Molecular Weight]
232.28 |
| Chemical Properties | Back Directory | [Melting point ]
104-105 °C | [Boiling point ]
393.8±52.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
7.58±0.20(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
Neocryptolepine (Cryptotackieine) has antiplasmodial activity. Neocryptolepine also shows antibacterial activity against Gram-positive bacteria (MIC < 100 μg/mL), and antifungal activity[1][2]. | [References]
[1] Pilar M. Fresneda, et al. A divergent approach to cryptotackieine and cryptosanguinolentine alkaloids.
[2] Cimanga K, et al. Antibacterial and antifungal activities of neocryptolepine, biscryptolepine and cryptoquindoline, alkaloids isolated from Cryptolepis sanguinolenta. Phytomedicine. 1998 May;5(3):209-14. DOI:10.1016/S0944-7113(98)80030-5 |
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