| Identification | Back Directory | [Name]
CP 84364 | [CAS]
114457-62-4 | [Synonyms]
364
CP 84
CP 84364
L-Phenylalanine, N-(4-morpholinylcarbonyl)- | [Molecular Formula]
C14H18N2O4 | [MDL Number]
MFCD00799236 | [MOL File]
114457-62-4.mol | [Molecular Weight]
278.3 |
| Hazard Information | Back Directory | [Description]
CP 84364 is a metabolite of CP-80794. | [Uses]
Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25 μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities. | [References]
[1] Quantitation of 4-cyclohexyl-2-hydroxy-3-(3-methylsulfanyl-2-{2- [(morpholine-4-carbonyl)amino]-3- phenylpropionylamino}propionylamino)butyric acid isopropyl ester (CP-80,794), a renin inhibitor, and its hydrolytic cleavage metabolite 2-[(morpholine-4-carbonyl)amino]-3-phenylpropionic acid (CP-84,364) in dog and human plasma by high-performance liquid chromatography |
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