| Identification | Back Directory | [Name]
Spiramine A | [CAS]
114531-28-1 | [Synonyms]
Spiramine A
Spiraenine A
12aH,14H-3,14a-Ethano-14,4b,8-ethanylylidene-1H,5H-[2]benzopyrano[4,3-g]oxazolo[3,2-a]azocin-1-ol,decahydro-8-methyl-2-methylene-, acetate (ester), (1S,3S,4aR,4bR,8R,8aS,12aS,14R,14aR,18R)- | [Molecular Formula]
C24H33NO4 | [MDL Number]
MFCD17214816 | [MOL File]
114531-28-1.mol | [Molecular Weight]
399.53 |
| Hazard Information | Back Directory | [Uses]
Spiramine A (Spiramine C acetate (ester)) is a diterpene alkaloid with antitumor and antimicrobial activity. Spiramine A inhibits PAF-induced rabbit platelet aggregation in a concentration-dependent manner, with an IC50 vallue of 6.7 μM[1]. | [Definition]
ChEBI: Spiramine A is a diterpenoid. It derives from a hydride of an atisane. | [References]
[1] Li L, et al. Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica. Eur J Pharmacol. 2002 Aug 2;449(1-2):23-8. DOI:10.1016/s0014-2999(02)01627-8 |
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