| Identification | Back Directory | [Name]
Methanone, [1-[4-[3-[(2R)-2-methyl-1-pyrrolidinyl]propoxy]phenyl]-1H-pyrazol-4-yl]-4-morpholinyl-, hydrochloride (1:1) | [CAS]
1152749-07-9 | [Synonyms]
Enerisant HCl
Enerisant hydrochloride | [Molecular Formula]
C22H30N4O3.ClH | [MOL File]
1152749-07-9.mol | [Molecular Weight]
434.96 |
| Hazard Information | Back Directory | [Uses]
Enerisant (TS-091) hydrochloride is a potent, highly selective, competitive and orally active histamine H3 receptor antagonist/inverse agonist with IC50s of 2.89 nM and 14.5 nM against human and rat histamine H3 receptors, respectively[1]. | [References]
[1] Hino N, et al. A novel potent and selective histamine H3 receptor antagonist enerisant: in vitro profiles, in vivo receptor occupancy, and wake-promoting and procognitive effects in rodents. Journal of Pharmacology and Experimental Therapeutics, 2020, 375(2): 276-285. |
|
|