| Identification | Back Directory | [Name]
DiMethyl bicyclo[1.1.1]pentane-1,3-dicarboxylate | [CAS]
115913-32-1 | [Synonyms]
DiMethyl bicyclo[1.1.1]pentane-1,3-dicarboxylate
1,3-dimethyl bicyclo[1.1.1]pentane-1,3-dicarboxylate
Dimethyl Bicyclo[1.1.1]Pentane-1,3-Dicarboxylate(WX120557)
Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid, dimethyl ester
BICYCLO[1.1.1]PENTANE-1,3-DICARBOXYLIC ACID, 1,3-DIMETHYL ESTER
1,1'-Bicyclo[1,1,1]pentane-1,3-dicarboxylic acid dimethyl ester | [Molecular Formula]
C9H12O4 | [MDL Number]
MFCD23106317 | [MOL File]
115913-32-1.mol | [Molecular Weight]
184.19 |
| Chemical Properties | Back Directory | [Boiling point ]
233.8±20.0 °C(Predicted) | [density ]
1.369±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Uses]
Dimethyl Bicyclo[1.1.1]pentane-1,3-dicarboxylate is a useful reagent for preparation of terminally functionalized [n]staffanes. | [Synthesis]
The crude product of compound 6 obtained in the previous step was directly dissolved in methanol (200 mL) and heated to reflux for 4 hours. After completion of the reaction, the reaction solution was concentrated to obtain the crude product of compound 7. Crystallization and purification was carried out by petroleum ether to finally obtain the pure compound 7 (12.2 g) in 90% yield. | [References]
[1] Journal of Medicinal Chemistry, 1996, vol. 39, # 15, p. 2874 - 2876
[2] Bioorganic and Medicinal Chemistry, 2001, vol. 9, # 2, p. 221 - 227
[3] Journal of Medicinal Chemistry, 2012, vol. 55, # 7, p. 3414 - 3424
[4] Patent: CN105294442, 2016, A. Location in patent: Paragraph 0006; 0014 |
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