| Identification | Back Directory | [Name]
Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[4-(acetylamino)-2-oxo-1(2H)-pyrimidinyl]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl ester | [CAS]
1159174-80-7 | [Synonyms]
N4-Ac-C-(S)-GNA phosphoramidite
N4-acetyl-(S)-1- (4, 4'-dimethoxytrityl)-3-cytidine-2-cyanoethyl Phosphoramidite
(S)-1-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl)diisopropylphosphoramidite
Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[4-(acetylamino)-2-oxo-1(2H)-pyrimidinyl]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl ester | [Molecular Formula]
C39H48N5O7P | [MOL File]
1159174-80-7.mol | [Molecular Weight]
729.81 |
| Chemical Properties | Back Directory | [pka]
10.43±0.20(Predicted) | [InChIKey]
GJBIWQXFRRQYML-MVYUDSRYNA-N | [SMILES]
C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H](CN1C=CC(NC(=O)C)=NC1=O)OP(OCCC#N)N(C(C)C)C(C)C |&1:25,r| |
| Hazard Information | Back Directory | [Uses]
N4-Ac-C-(S)-GNA phosphoramidite is an important intermediate for the synthesis of nucleic acids and their analogs[1]. | [References]
[1] Christensen MS, et al. Synthetic nucleic acid secondary structures containing the four stereoisomers of 1,4-bis(thymine-1-yl)butane-2,3-diol. Org Biomol Chem. 2008 Jan 7;6(1):81-91. DOI:10.1039/b713888a |
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