| Identification | Back Directory | [Name]
4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl... | [CAS]
1159408-65-7 | [Synonyms]
Tri-GalNAc(OAc)3 TFA
6-Amino-11,17-dioxo-6-[[3-o..
6-Amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-4,8-dioxa-12,16-diazaheneicosanamide 2,2,2-trifluoroacetate | [Molecular Formula]
C81H129F3N10O38 | [MOL File]
1159408-65-7.mol | [Molecular Weight]
1907.95 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C, sealed storage, away from moisture and light | [solubility ]
DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/mlPBS (pH 7.2): Soluble: =10 mg/ml | [solubility ]
DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml | [form ]
Oil | [color ]
White to off-white | [InChIKey]
ZQQFLUVDYMPTBZ-FCGQNKRGNA-N |
| Hazard Information | Back Directory | [Uses]
Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera[1]. | [References]
[1] Ahn G, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021 Sep;17(9):937-946. DOI:10.1038/s41589-021-00770-1 |
|
| Company Name: |
shanghai Kezx Gold
|
| Tel: |
18017817217 13770021960 |
| Website: |
http://www.kezxbio.com/ |
|