| Identification | Back Directory | [Name]
N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE | [CAS]
1161205-27-1 | [Synonyms]
PHCCC
N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE
(1aS,7E,7aS)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide
(1aS,7E,7aS)-7,7a-Dihydro-7-(hydroxyimino)-N-phenylbenzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide
Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, 7,7a-dihydro-7-(hydroxyimino)-N-phenyl-, (1aS,7E,7aS)- | [Molecular Formula]
C17H14N2O3 | [MDL Number]
MFCD00947860 | [MOL File]
1161205-27-1.mol | [Molecular Weight]
294.3 |
| Hazard Information | Back Directory | [Biological Activity]
Group I metabotropic glutamate receptor antagonist (IC 50 ~ 3 μ M); 67 times more potent than (S)-4-carboxyphenylglycine ((S)-4-Carboxyphenylglycine). Also a positive allosteric modulator for mGlu 4a ; potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission in vitro . Displays antiParkinsonian effects in rats in vivo . |
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