| Identification | Back Directory | [Name]
Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]- | [CAS]
1162665-52-2 | [Synonyms]
Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]- | [Molecular Formula]
C24H37N4O6PS | [MOL File]
1162665-52-2.mol | [Molecular Weight]
540.61 |
| Hazard Information | Back Directory | [Uses]
IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies[1]. | [References]
[1] Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor |
|
|