| Chemical Properties | Back Directory | [Boiling point ]
412.9±45.0 °C(Predicted) | [density ]
1.13±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Oil | [pka]
8.23±0.20(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Uses]
Seliforant (SENS-111) is a selective and orally histamine H4 receptor antagonist. | [storage]
Store at -20°C | [References]
[1] Petremann M, Gueguen C, Delgado Betancourt V, Wersinger E, Dyhrfjeld-Johnsen J. Effect of the novel histamine H4 receptor antagonist SENS-111 on spontaneous nystagmus in a rat model of acute unilateral vestibular loss. Br J Pharmacol. 2020;177(3):623-633. DOI:10.1111/bph.14803
[2] Venail F, Attali P, Wersinger E, Gomeni R, Poli S, Schmerber S. Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modelling of the novel H4 receptor inhibitor SENS-111 using a modified caloric test in healthy subjects. Br J Clin P DOI:10.1111/bcp.13744 |
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