| Identification | Back Directory | [Name]
8-[3-(3,4-dimethoxyphenyl)acryloyl]-7-hydroxy-4-methyl-2H-chromen-2-one | [CAS]
1164457-99-1 | [Synonyms]
CID7309015
CID-7309015
CID 7309015
8-[3-(3,4-dimethoxyphenyl)acryloyl]-7-hydroxy-4-methyl-2H-chromen-2-one | [Molecular Formula]
C21H18O6 | [MOL File]
1164457-99-1.mol | [Molecular Weight]
366.364 |
| Hazard Information | Back Directory | [Description]
CID-7309015 is an inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1), delayed death of the malarial parasite plasmid, the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1), ROR gamma transcriptional activity, and Hepatitis C Virus (HCV). | [Uses]
CID 7309015 is an inhibitor of retinoic acid-related orphan receptor gamma (ROR-γ). CID 7309015 can be used for research of inflammation, NF-κB signaling or inflammatory arthritis[1]. | [IC 50]
ROR-γ | [References]
[1] Li G, et al; Rheumatoid Arthritis Consortium International (RACI); Gupta N, Clemons PA, Stahl E, Tolliday N, Plenge RM. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. PLoS Genet. 2013 May;9(5):e1003487. DOI:10.1371/journal.pgen.1003487 |
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