| Identification | Back Directory | [Name]
MALONYL COENZYME A TETRALITHIUM SALT | [CAS]
116928-84-8 | [Synonyms]
Malonyl-CoA tetralithium salt
Malonyl coenzyme A tetralithium
MALONYL COENZYME A TETRALITHIUM SALT
Malonyl coenzyme A tetralithium salt >=90% (HPLC)
Coenzyme A, S-(hydrogenpropanedioate), tetralithium salt (9CI) | [EINECS(EC#)]
208-353-4 | [Molecular Formula]
C24H34Li4N7O19P3S | [MDL Number]
MFCD00221554 | [MOL File]
116928-84-8.mol | [Molecular Weight]
877.31 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: 50 mg/mL, clear, colorless | [form ]
solid | [Water Solubility ]
H2O: 50mg/mL, clear, colorless | [InChIKey]
DQLXXYMNINXQSV-QTRRCMKVSA-J | [SMILES]
[Li+].[Li+].[Li+].[Li+].CC(C)(COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n2cnc3c(N)ncnc23)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O |
| Hazard Information | Back Directory | [Uses]
Malonyl CoA (Malonyl coenzyme A) tetralithium is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA tetralithium is also a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1[1][2]. | [Biochem/physiol Actions]
Malonyl Coenzyme A is a Coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane. Malonyl CoA is formed by the Acetyl CoA Carboxylase-mediated carboxylation of acetyl CoA. | [References]
[1] B E Corkey, et at. A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells. J Biol Chem. 1989 Dec 25;264(36):21608-12. PMID:2689441 |
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