| Hazard Information | Back Directory | [Uses]
EMD 386088 Hydrochloride is a a 5-HT6 receptor agonist. | [in vivo]
EMD386088 (1, 5, 10 mg/kg) impairs both short-term memory (STM) and long-term memory (LTM) at 5 mg/kg, but produces no significant effects at 10 mg/kg in male Wistar rats[2].
EMD386088 (0, 2, 4 mg/kg) significantly impairs spontaneous alternation performancein at 2 mg/kg, but the high dose of 4 mg/kg dose not reach significance in C57BL/6J mice[3]. | [IC 50]
5-HT6 Receptor | [storage]
Desiccate at RT |
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