ChemicalBook--->CAS DataBase List--->1172089-00-7

1172089-00-7

1172089-00-7 Structure

1172089-00-7 Structure
IdentificationBack Directory
[Name]

M 1145
[CAS]

1172089-00-7
[Synonyms]

M 1145
[Molecular Formula]

C128H205N37O32
[MDL Number]

MFCD12912481
[MOL File]

1172089-00-7.mol
[Molecular Weight]

2774.23
Chemical PropertiesBack Directory
[density ]

1.45±0.1 g/cm3(Predicted)
[storage temp. ]

Desiccate at -20°C
[form ]

Powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 5 mg/ml in water
Hazard InformationBack Directory
[Uses]

M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM). M1145 has an additive effect on the signal transduction of galanin[1].
[References]

[1] Runesson J, Saar I, Lundstr?m L, J?rv J, Langel U. A novel GalR2-specific peptide agonist. Neuropeptides. 2009;43(3):187-192. DOI:10.1016/j.npep.2009.04.004
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