| Identification | Back Directory | [Name]
SCR-1481B1 | [CAS]
1174161-86-4 | [Synonyms]
SCR-1481B1
BMS-817378(tris)
c-Met inhibitor 2
QPFPEXKJGICONN-UHFFFAOYSA-N
SCR-1481B1(BMS-817378 tris salt)
SCR1481B1;BMS-817378;BMS817378;BMS 817378
N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-4-oxo-1-[(phosphonooxy)methyl]- (Tris salt) | [Molecular Formula]
C28H29ClF2N5O10P | [MOL File]
1174161-86-4.mol | [Molecular Weight]
699.99 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:8): 0.11 mg/ml; PBS (pH 7.2): slightly soluble | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SCR-1481B1 (Metatinib anhydrous) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor. | [IC 50]
VEGFR1 | [storage]
Store at -20°C | [References]
[1] Robert M. Borzilleri, et al. 4-pyridinone compounds and their use for cancer. WO/2009094417/A1. |
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