| Identification | Back Directory | [Name]
XENOPSIN-RELATED PEPTIDE 1 | [CAS]
117442-28-1 | [Synonyms]
XP-1
XENIN 8
Xenin-8 (huMan)
XENOPSIN-RELATED PEPTIDE 1
XENOPSIN-RELATED PEPTIDE I
HIS-PRO-LYS-ARG-PRO-TRP-ILE-LEU
H-HIS-PRO-LYS-ARG-PRO-TRP-ILE-LEU-OH
PHE-HIS-PRO-LYS-ARG-PRO-TRP-ILE-LEU: FHPKRPWIL
L-Leucine, L-histidyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl- | [Molecular Formula]
C51H79N15O9 | [MDL Number]
MFCD00167611 | [MOL File]
117442-28-1.mol | [Molecular Weight]
1046.27 |
| Chemical Properties | Back Directory | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
Powder | [pka]
3.41±0.10(Predicted) | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
His-Pro-Lys-Arg-Pro-Trp-Ile-Leu |
| Hazard Information | Back Directory | [Uses]
Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1]. | [storage]
Desiccate at -20°C | [References]
[1] Ramona A Silvestre, et al. Stimulatory effect of xenin-8 on insulin and glucagon secretion in the perfused rat pancreas. Regul Pept. 2003 Aug 15;115(1):25-9. DOI:10.1016/s0167-0115(03)00147-2 |
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