| Identification | Back Directory | [Name]
6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE | [CAS]
117491-83-5 | [Synonyms]
ROX NHS ester, 6- isomer
ROX NHS ester, pure 6- isomer
6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE
2,5-Pyrrolidinedione, 1-[[(2',3',6',7',12',13',16',17'-octahydro-3-oxospiro[isobenzofuran-1(3H),9'-[1H,5H,9H,11H,15H]xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin]-6-yl)carbonyl]oxy]- (9CI) | [Molecular Formula]
C37H33N3O7 | [MDL Number]
MFCD11858234 | [MOL File]
117491-83-5.mol | [Molecular Weight]
631.67 |
| Chemical Properties | Back Directory | [density ]
1.55±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMF, DMSO | [pka]
5.12±0.20(Predicted) | [Appearance]
Dark red solid | [ex/em]
575/603 nm | [ε(extinction coefficient)]
91000 L⋅mol−1⋅cm−1 | [Φ(quantum yield)]
1.0 | [InChIKey]
PLTIOQHKDXDXSK-UHFFFAOYSA-N | [SMILES]
N1(OC(C2=CC3C4(C5=C(C6=C7C(=C5)CCCN7CCC6)OC5=C6C7N(CCCC=7C=C54)CCC6)OC(=O)C=3C=C2)=O)C(=O)CCC1=O |
| Hazard Information | Back Directory | [Description]
ROX NHS ester, pure single isomer, is a rhodamine dye linker containing NHS ester group, which can be used to label the primary amines (-NH2) of proteins, oligonucleotides, and other amine-containing molecules. This dye can replace Alexa Fluor 568, Texas Red. | [Chemical Properties]
Appearance: Deep red solid
ex/em: 575/603 nm
Extinction coefficient (ε): 91000 L??mol??1??cm??1
Quantum yield (Φ): 1.0 | [Uses]
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer. | [Abs/Em Maxima]
570/591 nm | [Fluoresene quantum yield]
1 | [Extinction Coefficient]
88000 | [CF260]
0.62 | [CF280]
0.49 |
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