| Identification | Back Directory | [Name]
9-(2,4-dihydroxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-xanthene-1,8-dione | [CAS]
117593-36-9 | [Synonyms]
CIL 62
9-(2,4-dihydroxyphenyl)-3,3,6,6-tetramethyl-4,5,7,9-tetrahydro-2H-xanthene-1,8-dione | [Molecular Formula]
C23H26O5 | [MOL File]
117593-36-9.mol | [Molecular Weight]
382.45 |
| Chemical Properties | Back Directory | [Boiling point ]
583.7±50.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO: 125 mg/mL (326.84 mM) | [form ]
Solid | [pka]
9.16±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
CIL62 is a caspase-3/7-independent cell death inducer. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death[1]. | [References]
[1] Kenichi Shimada, et al. Global Survey of Cell Death Mechanisms Reveals Metabolic Regulation of Ferroptosis. Nat Chem Biol. 2016 Jul;12(7):497-503. DOI:10.1038/nchembio.2079 |
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