| Identification | Back Directory | [Name]
Sch 37370 | [CAS]
117796-52-8 | [Synonyms]
Sch 37370
N-AcylImpurity
Sch 37370 USP/EP/BP
N-Acetyldesloratadine
N-Acetyldesloratadine N
N-acetyl base loratadine
Desloratadine impurity III (Desloratadine n-acetyl impurity)"
1-(4-(8-chloro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(6H)-ylidene)piperidin-1-yl)ethanone
1-[4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidin-1-yl]ethanone
1-Acetyl-4-[(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin)-11-ylidene]piperidine
1-[4-[(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)-11-ylidene]piperidino]ethanone
Ethanone, 1-[4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-
1-(4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-yl)ethan-1-one | [Molecular Formula]
C21H21ClN2O | [MDL Number]
MFCD00873685 | [MOL File]
117796-52-8.mol | [Molecular Weight]
352.86 |
| Chemical Properties | Back Directory | [Melting point ]
155-157 °C | [Boiling point ]
546.9±50.0 °C(Predicted) | [density ]
1.257±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Solid | [pka]
4.16±0.20(Predicted) | [color ]
Off-White to Pale Pink | [Major Application]
pharmaceutical small molecule | [InChI]
InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3 | [InChIKey]
FLTBEMVEAFMWDD-UHFFFAOYSA-N | [SMILES]
C(=O)(N1CC/C(=C2\C3=NC=CC=C3CCC3=CC(Cl)=CC=C3\2)/CC1)C |
| Hazard Information | Back Directory | [Uses]
N-Acetyldesloratadine is an impurity in the synthesis of Desloratadine (D290250), Nonsedating-type histamine H1-receptor antagonist. |
|
|