ChemicalBook--->CAS DataBase List--->1180-35-4

1180-35-4

1180-35-4 Structure

1180-35-4 Structure
IdentificationBack Directory
[Name]

Acetylepipodophyllotoxin
[CAS]

1180-35-4
[Synonyms]

Acetylepipodophyllotoxin
Epipodophyllotoxin acetate
4-O-Epipodophyllotoxinyl acetate
Acetylepipodophyllotoxin/Epipodophyllotoxin acetate
(5S,5aR,8aR,9R)-8-Oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-ylacetate
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-(acetyloxy)-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9S)-
[Molecular Formula]

C24H24O9
[MDL Number]

MFCD20274734
[MOL File]

1180-35-4.mol
[Molecular Weight]

456.44
Hazard InformationBack Directory
[Uses]

Epipodophyllotoxin acetate (4-O-Epipodophyllotoxinyl acetate; compound 4) is a cyclolignan that exhibits antineoplastic and antiviral activities. Epipodophyllotoxin acetate inhibits HSV and VSV, with IC50s of 0.2 and 0.1 μg/mL, respectively[1].
[References]

[1] Feliciano AS, et, al. Antineoplastic and antiviral activities of some cyclolignans. Planta Med. 1993 Jun;59(3):246-9. DOI:10.1055/s-2006-959660
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