| Identification | Back Directory | [Name]
O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE | [CAS]
118021-35-5 | [Synonyms]
L-4-OXALYSINE HCL
H-SER(ETNH2)-OH HCL
H-LYS[*4(<-O)]-OH HCL
4-OXY-L-LYSINE HYDROCHLORIDE
L-4-Oxalysine (hydrochloride)
O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE
O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE USP/EP/BP
(2S)-2-amino-3-(2-aminoethoxy)propanoicacid,hydrochloride
(S)-(+)-2-AMINO-3-(2-AMINOETHOXY)PROPANOIC ACID, MONOHYDROCHLORIDE
(S)-(+)-2-AMINO-3-(2-AMINOETHOXY)-PROPAN OIC ACID HYDROCHLORIDE, 98% | [Molecular Formula]
C5H13ClN2O3 | [MDL Number]
MFCD01631149 | [MOL File]
118021-35-5.mol | [Molecular Weight]
184.62 |
| Chemical Properties | Back Directory | [Melting point ]
212-216 °C(lit.)
| [alpha ]
+4.0～+8.0°(c=10,dilHCl)(D/20) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
L-4-Oxalysine hydrochloride is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China which has shown antitumor activities. | [Biological Activity]
L-4-Oxalysine hydrochloride is a natural substance isolated from the culture medium of Streptomyces in China and has anticancer activity. | [in vitro]
L-4-oxalysine functionally antagonizes the a-fetoprotein-induced suppression of the mitogen- and one-way mixed lymphocyte culture-induced proliferation of spleen lymphocytes and interleukin-6 production by these cells in mice bearing the hepatoma-22 tumor. | [in vivo]
L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma. | [storage]
Store at -20°C | [References]
[1] Dai ZQ, et al. Effect of L-4-oxalysine on ultrastructures of liver cells in mice. Zhongguo Yao Li Xue Bao. 1991 Jul;12(4):336-40. PMID:1807083
[2] Wang XW, et al. Immunostimulatory action of L-4-oxalysine counteracts immunosuppression induced by alpha-fetoprotein. Eur J Pharmacol. 1998 Jun 12;351(1):105-11. DOI:10.1016/s0014-2999(98)00277-5 |
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