| Identification | Back Directory | [Name]
Retin-10,19,19,19-d4-ol | [CAS]
118063-12-0 | [Synonyms]
Vitamin A-D4
Retin-10,19,19,19-d4-ol
Vitamin A-d4 (Retinol-d4)
VITAMIN A (RETINOL) (95% CHEMICAL PURITY)(10,19,19,19-D4, 96%) (50 PPM BHT) | [Molecular Formula]
C20H30O | [MOL File]
118063-12-0.mol | [Molecular Weight]
286.46 |
| Chemical Properties | Back Directory | [form ]
Oil | [color ]
Colorless to light yellow | [InChI]
InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+ | [InChIKey]
FPIPGXGPPPQFEQ-OVSJKPMPSA-N | [SMILES]
C(/C1=C(CCCC1(C)C)C)=C\C(\C([H])([H])[H])=C(/[H])\C=C\C(\C)=C\CO | [CAS Number Unlabeled]
68-26-8 |
| Hazard Information | Back Directory | [Uses]
Vitamin A-d4 (Vitamin A1-d4; all-trans-Retinol-d4) is the deuterium labeled Vitamin A. Vitamin A is an endogenous metabolite. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Zhang M, et al. High-fat diet enhanced retinal dehydrogenase activity, but suppressed retinol dehydrogenase activity in liver of rats. J Pharmacol Sci. 2015 Apr;127(4):430-8. DOI:10.1016/j.jphs.2015.03.001
[3] Miyazaki H, et al. Retinol status and expression of retinol-related proteins in methionine-choline deficient rats. J Nutr Sci Vitaminol (Tokyo). 2014;60(2):78-85. DOI:10.3177/jnsv.60.78 |
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