| Identification | Back Directory | [Name]
KAROUNIDIOL | [CAS]
118117-31-0 | [Synonyms]
Aids064688
Aids-064688
KAROUNIDIOL
26-Noroleana-7,9(11)-diene-3,29-diol,13-methyl-, (3a,13a,14b,20a)-
26-Noroleana-7,9(11)-diene-3,29-diol, 13-methyl-, (3α,13α,14β,20α)-
26-Noroleana-7,9(11)-diene-3,29-diol, 13-methyl-, (3.alpha.,13.alpha., 14.beta.,20.alpha.)-
(3R,6Bs,8as,11R,12bs,14bs)-11-hydroxymethyl-4,4,6B,8A,11,12B,14B-heptamethyl-1,2,3,4,4A,5,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-octadecahydro-picen-3-ol | [Molecular Formula]
C29H46O2 | [MDL Number]
MFCD02752466 | [MOL File]
118117-31-0.mol | [Molecular Weight]
426.68 |
| Hazard Information | Back Directory | [Description]
Karounidiol exhibits cytotoxicity especially against a human renal cancer.
Karounidiol markedly suppresses the promoting effect of TPA (1 microgram/mouse) on skin tumor formation in mice following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse). | [Uses]
Karounidiol is a triterpenoid that can be found in Trichosanthes kirilowii. [1]. | [Definition]
ChEBI: Karounidiol is an organic hydroxy compound. | [References]
[1] Akihisa T, et al. Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines. Cancer Lett. 2001 Nov 8;173(1):9-14. DOI:10.1016/s0304-3835(01)00689-9 |
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
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