| Identification | Back Directory | [Name]
Retin-20,20,20-d3-ol, 15-acetate | [CAS]
118139-36-9 | [Synonyms]
ALK001
ALK-001
ALK 001
C-20D3vitamin A
C-20-D3-vitamin A
C-20-D3-Retinyl Acetate
Retin-20,20,20-d3-ol, 15-acetate | [Molecular Formula]
C22H32O2 | [MDL Number]
MFCD30738759 | [MOL File]
118139-36-9.mol | [Molecular Weight]
328.5 |
| Hazard Information | Back Directory | [Description]
ALK-001 is a vitamin A analog potentially for the treatment of Stargardt’s disease. | [Uses]
Retinyl acetate-d3 (ALK-001) is a deuterated Vitamin A. Retinyl acetate-d3 can be used for research of geographic atrophy (GA) secondary to age-related macular degeneration (AMD)[1]. | [References]
[1] Cargnin S, et al. A primer of deuterium in drug design. Future Med Chem. 2019 Aug;11(16):2039-2042. DOI:10.4155/fmc-2019-0183
[2] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110 |
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