| Identification | Back Directory | [Name]
tachyplesin | [CAS]
118231-04-2 | [Synonyms]
tachyplesin
Tachyplesin I (9CI)
Tachyplesin peptide, Tachypleus tridentatus
L-Argininamide, L-lysyl-L-tryptophyl-L-cysteinyl-L-phenylalanyl-L-arginyl-L-valyl-L-cysteinyl-L-tyrosyl-L-arginylglycyl-L-isoleucyl-L-cysteinyl-L-tyrosyl-L-arginyl-L-arginyl-L-cysteinyl-, cyclic (3→16),(7→12)-bis(disulfide) | [Molecular Formula]
C99H151N35O19S4 | [MOL File]
118231-04-2.mol | [Molecular Weight]
2263.74 |
| Hazard Information | Back Directory | [Uses]
Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane[1]. | [References]
[1] D V Kuzmin, et al. In Vitro Study of Antitumor Effect of Antimicrobial Peptide Tachyplesin I in Combination with Cisplatin. Bull Exp Biol Med. 2018 Jun;165(2):220-224. DOI:10.1007/s10517-018-4134-6 |
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