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118266-99-2

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118266-99-2 Structure

118266-99-2 Structure
IdentificationBack Directory
[Name]

IsodorsManin A
[CAS]

118266-99-2
[Synonyms]

IsodorsManin A
MicroorganismA
1-(3,4-Dihydro-5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(4-hydroxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-(3,4-dihydro-5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(4-hydroxyphenyl)-
[Molecular Formula]

C20H20O4
[MDL Number]

MFCD26406164
[MOL File]

118266-99-2.mol
[Molecular Weight]

324.37
Chemical PropertiesBack Directory
[Melting point ]

239-240℃
[Boiling point ]

549.9±50.0 °C(Predicted)
[density ]

1.233±0.06 g/cm3(Predicted)
[pka]

7.87±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Isodorsmanin A is an anti-inflammatory agent. Isodorsmanin A suppresses the production of inflammatory mediators and proinflammatory cytokines. Isodorsmanin A inhibits the phosphorylation of JNK, MAPK[1].
[References]

[1] Chung YC, et al. Isodorsmanin A Prevents Inflammatory Response in LPS-Stimulated Macrophages by Inhibiting the JNK and NF-κB Signaling Pathways. Curr Issues Mol Biol. 2023 Feb 13;45(2):1601-1612. DOI:10.3390/cimb45020103
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