| Identification | Back Directory | [Name]
1H-Pyrrolo3,2-fquinoline-2-carboxylic acid, 8-chloro-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)- | [CAS]
118292-35-6 | [Synonyms]
Brn 5689373 pyrindamycin B Duocarmycin C1 ILRQRCTVPANBBE-GWQKEKGPSA-N 1H-Pyrrolo(3,2-f)quinoline-2-carboxylic acid, 8-chloro-2,3,6,7,8,9-hex ahydro-4-hydroxy-2-methyl-oxo-6-((5,6,7-trimethoxy-1H-indol-2-yl)carbo nyl)-, methyl ester (2R)-8β-Chloro-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-ylcarbonyl)-1H-pyrrolo[3,2-f]quinoline-2α-carboxylic acid methyl ester 1H-Pyrrolo3,2-fquinoline-2-carboxylic acid, 8-chloro-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)- | [Molecular Formula]
C26H26ClN3O8 | [MDL Number]
MFCD00482954 | [MOL File]
118292-35-6.mol | [Molecular Weight]
543.95 |
| Chemical Properties | Back Directory | [Boiling point ]
805.6±65.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
8.79±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
Pyrindamycin B is an antibiotic, actives against gram-positive and gram-negative bacterias, and exhibits strong therapeutic effects against both agent-sensitive and resistant cells of P388 leukemia in mice[1]. | [References]
[1] Ohba K, et al. Pyrindamycins A and B, new antitumor antibiotics. J Antibiot (Tokyo). 1988 Oct;41(10):1515-9. DOI:10.7164/antibiotics.41.1515 |
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