ChemicalBook--->CAS DataBase List--->118421-50-4

118421-50-4

118421-50-4 Structure

118421-50-4 Structure
IdentificationBack Directory
[Name]

GLUTATHIONE MONOETHYL ESTER
[CAS]

118421-50-4
[Synonyms]

GSH-MEE
GSH-OEt
GAMMA-GCE
GLU(CYS-GLY-OET)
GAMMA-GLU-CYS-GLY-OET
GLUTATHIONE MONOETHYL ESTER
glutathione reduced ethyl ester
L-GLUTATHIONE REDUCED ETHYL ESTER
GLUTATHIONE-MONOETHYL ESTER (REDUCED)
GLUTATHIONE, REDUCED FORM ETHYL ESTER
L-GAMMA-GLUTAMYL-L-CYSTEINYL ETHYL GLYCINATE
γ-l-glutamyl-l-cysteinyl-glycine ethyl ester
GAMMA-L-GLUTAMYL-L-CYSTEINYL-GLYCINE ETHYL ESTER
N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine monoethyl ester
Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-, monoethyl ester
[Molecular Formula]

C12H21N3O6S
[MDL Number]

MFCD00156117
[MOL File]

118421-50-4.mol
[Molecular Weight]

335.38
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

water: 50 mg/mL
[form ]

solid
[color ]

white
[Water Solubility ]

water: 50mg/mL
[InChI]

1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1
[InChIKey]

JKRODHBGNBKZLE-YUMQZZPRSA-N
[SMILES]

SC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)NCC(=O)OCC
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P271-P280
[WGK Germany ]

3
[HS Code ]

2930909899
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Glutathione reduced ethyl ester has been shown to be much more easily transported into isolated rat hepatocytes than glutathione. Within the cells it could be converted into reduced glutathione. Therefore it could - better than glutathione - prevent immun
[General Description]

Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Effective transport of GSH-MEE has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. A protective agent against cellular damage, such as cataracts and mitochondrial degeneration.
[Biochem/physiol Actions]

Primary TargetEffective transport of GSH-MEE
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